Natural Quercetin, Pure Encapsulation, 60’s

Pure Encapsulation Natural Quercetin:

• Features pure quercetin derived from a natural plant source
• Quercetin is one of the most bioactive and best studied bioflavonoids
• Each vegetarian capsule provides 250 mg of quercetin
• Research suggests a supportive role for cellular and immune health

Ingredients: Quercetin, hypoallergenic plant fibre (microcrystalline cellulose). Vegetarian capsule (hydroxypropyl methyl cellulose).

Please note: This product cannot be delivered to some countries.
( Algeria, Andorra, Anguilla, Azores, Bahrain, Bangladesh, Burkina Faso, Cameroon, Canada, Cayman Islands, Ethiopia, Georgia. Ghana, Gibraltar, Greenland, Hong Kong, Iceland, India, Iraq, Israel, Japan, Kenya, Kuwait, Lebanon, Lesotho, Liechtenstein. Macau, Madagascar, Madeira, Malawi, Malaysia, Martinique, Monaco, Montserrat, Morocco, Namibia, Netherlands Antilles. New Zealand, Nigeria, Norway, Puerto Rico, Qatar, Rwanda, San Marino, Saudi Arabia, Senegal, Serbia, Singapore, South Africa. South Korea, Taiwan, Tanzania, United Republic Of, Thailand, Togo, Tunisia, United Arab Emirates )

Study:

This article shows the potential benefit of using quercetin in covid 19 patients. Quercetin also shows a zinc ionophore activity. This is from that study: “Labile zinc, a tiny fraction of total intracellular zinc that is loosely bound to proteins and easily interchangeable, modulates the activity of numerous signalling and metabolic pathways. Dietary plant polyphenols such as the flavonoids quercetin (QCT) and epigallocatechin-gallate act as antioxidants and as signalling molecules. Remarkably, the activities of numerous enzymes that are targeted by polyphenols are dependent on zinc. We have previously shown that these polyphenols chelate zinc cations and hypothesized that these flavonoids might be also acting as zinc ionophores, transporting zinc cations through the plasma membrane.

To prove this hypothesis, herein, we have demonstrated the capacity of QCT and epigallocatechin-gallate to rapidly increase labile zinc in mouse hepatocarcinoma Hepa 1-6 cells as well as, for the first time, in liposomes. In order to confirm that the polyphenols transport zinc cations across the plasma membrane independently of plasma membrane zinc transporters, QCT, epigallocatechin-gallate, or clioquinol (CQ), alone and combined with zinc, were added to unilamellar dipalmitoylphosphocholine/cholesterol liposomes loaded with membrane-impermeant FluoZin-3. Only the combinations of the chelators with zinc triggered a rapid increase of FluoZin-3 fluorescence within the liposomes, thus demonstrating the ionophore action of QCT, epigallocatechin-gallate, and CQ on lipid membrane systems. The ionophore activity of dietary polyphenols may underlay the raising of labile zinc levels triggered in cells by polyphenols and thus many of their biological actions.”