Organic Myco-Zen, Mushrooms 4 Life, 60s

This Organic Myco-Zen Mushrooms complex is produced to the highest standards and ingredients cultivated as nature intended.

Reishi has adoptogenic properties and known as the mushroom of Immortality. Its spores are very nutrients dense and may have anti-inflammatory and immunological properties.

Lion’s Mane, also sometime referred to as the the “Mountain Priest”, is packed with NGF, which may stimulate nerve cells growth, especially in the Hippocampus area of the brain.

Organic Myco-Zen Ingredients: Organic reishi (Ganoderma lucidum) fruiting body extract powder*. Organic lion’s mane (Hericium erinaceus) fruiting body extract powder*, vegetable cellulose capsule (hydroxypropyl methylcellulose)

Study:

This is a study on the promoting activity of Lion’s Mane on the growth and differentiation of neurons, by increasing nerve growth factor. From that study: “Neurotrophic factors are important in promoting the growth and differentiation of neurons. Nerve growth factor (NGF) is essential for the maintenance of the basal forebrain cholinergic system. Hericenones and erinacines isolated from the medicinal mushroom Hericium erinaceus can induce NGF synthesis in nerve cells. In this study, we evaluated the synergistic interaction between H. erinaceus aqueous extract and exogenous NGF on the neurite outgrowth stimulation of neuroblastoma-glioma cell NG108-15. The neuroprotective effect of the mushroom extract toward oxidative stress was also studied. Aqueous extract of H. erinaceus was shown to be non-cytotoxic to human lung fibroblast MRC-5 and NG108-15 cells.

The combination of 10 ng/mL NGF with 1 μg/mL mushroom extract yielded the highest percentage increase of 60.6% neurite outgrowth. The extract contained neuroactive compounds that induced the secretion of extracellular NGF in NG108-15 cells, thereby promoting neurite outgrowth activity. However, the H. erinaceus extract failed to protect NG108-15 cells subjected to oxidative stress when applied in pre-treatment and co-treatment modes. In conclusion, the aqueous extract of H. erinaceus contained neuroactive compounds which induced NGF-synthesis and promoted neurite outgrowth in NG108-15 cells. The extract also enhanced the neurite outgrowth stimulation activity of NGF when applied in combination. The aqueous preparation of H. erinaceus had neurotrophic but not neuroprotective activities.”